AAP eBooks

2015 Nelson's Pediatric Antimicrobial Therapy, 21st Edition

Edited by John S. Bradley, MD, FAAP and David W. Kimberlin, MD, FAAP

New! This bestselling and widely used resource on pediatric antimicrobial therapy provides instant access to reliable, up-to-the-minute recommendations for treatment of all infectious diseases in children.

For each disease, the authors provide a commentary to help health care providers select the best of all antimicrobial choices. Drug descriptions cover all antimicrobial agents available today, and include complete information about dosing regimens.

In response to growing concerns about overuse of antibiotics, the book includes guidelines on when not to prescribe antimicrobials.

Key 21st edition features!

  • New at-a-glance tables that provide a quick overview of bacterial and fungal pathogen susceptibilities to commonly used antimicrobials

  • New information on neonatal developmental pharmacology

  • Information on the strength and level of evidence for all treatment recommendations

  • Therapies for specific pathogens - bacterial, fungal, viral, parasitic

  • Chapter on antibiotic therapy for children who are obese

  • Chapter on antimicrobial prophylaxis and prevention of symptomatic infection

  • Balanced information on safety, efficacy, and tolerability

  • Updated drug cost and availability data

  • Maximal adult dosages and higher dosages of some antimicrobials commonly used in children

  • Guidelines on when not to use antimicrobials


  • 1. Choosing Among Antibiotics Within a Class: Beta-lactams, Macrolides, Aminoglycosides, and Fluoroquinolones

  • 2. Choosing Among Antifungal Agents: Polyenes, Azoles, and Echinocandins

  • 3. How Antibiotic Dosages Are Determined Using Susceptibility Data, Pharmacodynamics, and Treatment Outcomes

  • 4. Community-Associated Methicillin-Resistant Staphylococcus aureus

  • 5. Antimicrobial Therapy for Newborns

    • A. Recommended Therapy for Selected Newborn Conditions

    • B. Antimicrobial Dosages for Neonates

    • C. Aminoglycosides

    • D. Vancomycin

    • E. Use of Antimicrobials During Pregnancy or Breastfeeding

  • 6. Antimicrobial Therapy According to Clinical Syndromes

    • A. Skin and Soft Tissue Infections

    • B. Skeletal Infections

    • C. Eye Infections

    • D. Ear and Sinus Infections

    • E. Oropharyngeal Infections

    • F. Lower Respiratory Tract Infections

    • G. Cardiovascular Infections

    • H. Gastrointestinal Infections

    • I. Genital and Sexually Transmitted Infections

    • J. Central Nervous System Infections

    • K. Urinary Tract Infections

    • L. Miscellaneous Systemic Infections

  • 7. Preferred Therapy for Specific Bacterial and Mycobacterial Pathogens

    • A. Common Bacterial Pathogens and Usual Pattern of Susceptibility to Antibiotics (Gram Positive)

    • B. Common Bacterial Pathogens and Usual Pattern of Susceptibility to Antibiotics (Gram Negative)

    • C. Common Bacterial Pathogens and Usual Pattern of Susceptibility to Antibiotics (Anaerobes)

    • D. Preferred Therapy for Specific Bacterial and Mycobacterial Pathogens

  • 8. Preferred Therapy for Specific Fungal Pathogens

    • A. Overview of Fungal Pathogens and Usual Pattern of Susceptibility to Antifungals

    • B. Systemic Infections

    • C. Localized Mucocutaneous Infections

  • 9. Preferred Therapy for Specific Viral Pathogens

    • A. Overview of Non-HIV Viral Pathogens and Usual Pattern of Susceptibility to Antivirals

    • B. Preferred Therapy for Specific Viral Pathogens

  • 10. Preferred Therapy for Specific Parasitic Pathogens

  • 11. Alphabetic Listing of Antimicrobials

    • A. Systemic Antimicrobials With Dosage Forms and Usual Dosages

    • B. Topical Antimicrobials (Skin, Eye, Ear)

  • 12. Antibiotic Therapy for Obese Children

  • 13. Sequential Parenteral-Oral Antibiotic Therapy (Oral Step-down Therapy) for Serious Infections

  • 14. Antimicrobial Prophylaxis/Prevention of Symptomatic Infection

    • A. Postexposure Prophylaxis

    • B. Long-term Symptomatic Disease Prophylaxis

    • C. Preemptive Treatment/Latent Infection Treatment ("Prophylaxis of Symptomatic Infection")

    • D. Surgical/Procedure Prophylaxis

  • 15. Adverse Reactions to Antimicrobial Agents

  • 16. Drug Interactions

  • Appendix: Nomogram for Determining Body Surface Area

  1. Page vii
    1. Page 39
    2. Page 39
    1. Page 49
  2. Page 217
  3. Page 237

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